Downstream Process Development Engineer, Bioproduction (Plainville, MA)
$96k/y-$127k/y
Thermo Fisher Scientific2 days ago
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OnsiteFull-timeSenior
Summary
Thermo Fisher Scientific is seeking a Downstream Process Development Engineer to join their team in Plainville, MA. The role involves supporting development, scale-up, and customer enablement of downstream purification processes using single-use and hybrid purification platforms.
About the Role
As a Downstream Process Development Engineer, you will be responsible for developing and executing downstream purification processes, performing large-scale protein purification, troubleshooting chromatography columns, and collaborating with cross-functional teams. Your daily tasks will include making real-time process adjustments, generating technical data, and leading customer training and demonstrations.
About You
Required:
- B.S. in Chemical Engineering, Biochemistry, Biotechnology, or related field with 5+ years of relevant experience.
- Hands-on experience with protein purification using chromatography, including capture, intermediate, and polishing steps.
- Direct experience operating large-scale chromatography columns (≥30 cm ID).
- Strong ability to diagnose chromatography performance issues, including pressure, flow, and resin behavior.
Preferred:
- Experience operating chromatography columns 45-60 cm ID at pilot or manufacturing scale.
- Hands-on experience with resin lifetime studies and column performance trending across multiple cycles.
- Understanding of resin selection tradeoffs and cleaning practices for chromatography resins.
- Experience operating chromatography skids using DeltaV.
Benefits
- A choice of national medical and dental plans, and a national vision plan.
- Employee assistance and family support programs, including commuter benefits and tuition reimbursement.
- At least 120 hours paid time off (PTO) and 10 paid holidays annually.
- Retirement and savings programs, including a competitive 401(k) U.S. retirement savings plan.
- Employees' Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount.
Thermo Fisher Scientific
The world leader in serving science To serve science, Thermo Fisher Scientific needs to stay ahead of it, we need to anticipate customer needs. We need to constantly think about advancing science, so customers have the freedom to be bolder and more innovative – we are committed to pushing science and technology a step beyond where it is today. To enable our customers to make the world healthier, cleaner and safer
Milford, MA