BioSpace is seeking a Principal Scientist - Cancer Vaccines to join their team in Englewood, NJ. The role involves leading the Cancer Prevention Group in researching and developing novel preventive cancer vaccines.
About the Role
As a Principal Scientist, you will be responsible for spearheading research initiatives focused on peptide-based vaccine development and cancer immunology. Your tasks will include leading the development of personalized cancer vaccines, overseeing vaccine epitope identification, and managing external projects with CROs. You will also be involved in immune response monitoring and the application of various vaccine delivery systems.
About You
Required:
A PhD, MD or both and at least 10 years of vaccine development experience, preferably in cancer vaccines.
In-depth knowledge of personalized cancer vaccines, including peptide-based and neoantigen-based vaccines.
Extensive experience with vaccine epitope identification, selection/prioritization, vaccine adjuvants, and immune response monitoring.
Experience with molecular T cell receptor repertoire analysis, T cell proliferation assays, cytokine release assays, and ELISPOT.
Experience deriving antigen-specific T cell clones and lines.
Expertise in cancer stem cell antigens, tumor-associated antigens, neoantigens, immuno-editing, and immuno-monitoring.
Extensive knowledge of vaccine delivery systems, including peptide-, cell-, and viral-based systems.
Preferred:
The ability to work well with CROs and manage external projects.
An easygoing, hard-working personality.
Benefits
Competitive salary with a starting base pay range of $165k–$205k.
Additional compensation ranging from $7,500 to $20,000.
BioSpace
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