Principal Scientist, Lentivirus Downstream Process Development
$142k/y-$186k/y
BioSpace21 hours ago
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OnsiteFull-timeSenior
Summary
Legend Biotech is seeking a Principal Scientist, Lentivirus Downstream Process Development to join their Technical Development team in Somerset, NJ. The role involves designing, optimizing, and scaling purification processes for lentiviral vectors to support advanced cell therapy programs.
About the Role
As a Principal Scientist, you will be responsible for developing purification strategies for lentiviral vectors, ensuring robust and scalable processes for GMP manufacturing. You will lead the optimization of downstream processes, provide training, and guide a team of scientists while ensuring compliance with regulatory requirements.
About You
Required:
- Advanced degree (PhD preferred, or MS) in Chemical Engineering, Biomedical Engineering, Virology, Molecular Biology, or a related field.
- 8+ years (PhD) or 10+ years (MS) of experience in process development or manufacturing within a biotech or pharmaceutical setting.
- Deep technical hands-on experience in purification, chromatography, and TFF specifically for viral vectors.
Preferred:
- Experience in developing vector processes tailored for CAR-T generation and systemic delivery.
- Experience in handling large scale (>50L) purification processes.
- Language: English. Mandarin is a plus.
Benefits
- Medical, dental, and vision insurance.
- 401(k) retirement plan with a company match that vests fully on day one.
- Eight (8) weeks of paid parental leave after just three (3) months of employment.
- Paid time off policy including vacation time, personal time, sick time, floating holidays, and eleven (11) company holidays.
- Voluntary benefits including flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage.
BioSpace
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Somerset, NJ