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Job Analysis:
The Senior Director, Medical Operations and Analytics role at Day One Biopharmaceuticals is fundamentally designed to orchestrate operational excellence within the Medical Affairs function, ensuring that complex strategic and tactical deliverables are executed efficiently and with high quality. This leadership role goes beyond routine project management; it requires deep expertise in aligning cross-functional Medical Affairs initiatives—from strategic planning and evidence generation to compliance and inspection readiness—within a dynamic, fast-paced biotech environment. The candidate must navigate the nuances of external vendor management, budget oversight, and regulatory compliance, balancing operational rigor with agility and innovation. Success in this role involves not only mastering detailed processes such as MLR review and FMV assessments but also fostering high-performance teams and driving continuous improvement across medical operations. The candidate will face challenges inherent to the biotech industry, including evolving regulatory landscapes, multi-stakeholder coordination, and the pressure to accelerate treatment innovations for urgent, unmet medical needs. Key qualifications such as 12+ years in Medical Affairs with leadership exposure, strong project management skills, and a strategic mindset are crucial because they enable the director to effectively influence outcomes, ensure accountability, and contribute to Day One’s mission-driven goals. The role demands autonomous decision-making on priorities, resource allocation, and responsiveness to emergent operational issues, with an expectation to deliver measurable impact on operational efficiency and organizational readiness within the first year.
Company Analysis:
Day One Biopharmaceuticals occupies a distinctive niche as a commercial-stage biotech company committed to pioneering first- or best-in-class medicines that address both childhood and adult diseases, with a special emphasis on accelerating treatments for pediatric cancers. Positioned as an innovative and mission-driven disruptor in a traditionally slow-moving sector, Day One’s culture likely emphasizes urgency, scientific rigor, and a compassionate patient-centric focus. This translates into a workplace where operational agility and compliance are paramount, as is the ability to work collaboratively across functions in a high-stakes, impact-driven environment. The Senior Director role reports directly to the VP of Medical Affairs, suggesting significant visibility and influence within a relatively lean organization. The company’s strategic emphasis on rapid R&D translation and early intervention therapies means that this role is a critical strategic hire for scaling operational capabilities to match high growth ambitions and regulatory demands. Candidates should anticipate a culture that rewards initiative, precision, and integrity, while being supportive of innovation and responsiveness to patient needs. Given Day One’s equity in cutting-edge, unmet medical needs, an alignment with its core values of speeding development while ensuring quality will be essential for long-term fit and success.
